Formulation evidence record
Seachem Cupramine
External parasite treatment (copper-amine) · US formulation
Shrimp
Amano, cherry, crystal and other freshwater shrimp.
Snails
Nerite, mystery, ramshorn and other aquarium snails.
Live plants
Rooted and floating live aquarium plants.
Marine invertebrates
Corals, anemones, starfish and marine crustaceans.
Biological filter
The nitrifying bacteria in your filter media.
Not addressed by the manufacturer for: scaleless fish. No statement was found, so no verdict is given — that is not a clearance.
Why FishyMag says this
The manufacturer's own wording, quoted rather than paraphrased, so you can judge it yourself.
Shrimp
Manufacturer advises againstSeachem instructs keepers to remove all invertebrates before treatment, describing them as extremely sensitive to copper.
Contains copper, with a source-linked caution associated with this group. This raises a flag—it is not the basis of the verdict above.
“Remove all invertebrates - these are extremely sensitive to copper and will not tolerate treatment with a copper-based medication.”
manufacturer page · seachem.com · checked August 16, 2026
Snails
Manufacturer advises againstSnails are invertebrates and fall under the same instruction to remove all invertebrates before treatment.
Contains copper, with a source-linked caution associated with this group. This raises a flag—it is not the basis of the verdict above.
“Remove all invertebrates - these are extremely sensitive to copper and will not tolerate treatment with a copper-based medication.”
manufacturer page · seachem.com · checked August 16, 2026
Live plants
No evidence foundSeachem does not address live plants in its Cupramine documentation. No statement was found either way, so this stays unknown rather than being assumed safe.
No manufacturer statement was found for this group. That is not the same as a clearance — treat it as unconfirmed and ask the manufacturer before dosing.
Marine invertebrates
Manufacturer advises againstCovered by the same blanket instruction to remove all invertebrates.
Contains copper, with a source-linked caution associated with this group. This raises a flag—it is not the basis of the verdict above.
“Remove all invertebrates - these are extremely sensitive to copper and will not tolerate treatment with a copper-based medication.”
manufacturer page · seachem.com · checked August 16, 2026
Biological filter
No evidence foundSeachem does not address effects on biological filtration in its Cupramine documentation.
No manufacturer statement was found for this group. That is not the same as a clearance — treat it as unconfirmed and ask the manufacturer before dosing.
Product details
- Manufacturer states it treats
- Ich, Velvet, External protozoan parasites
- Chemical filtration
- Remove chemical filtration during treatment
- Ingredients as stated
- Copper-amine complex. Dosed to 0.5 mg/L in saltwater and 0.25 mg/L in freshwater, held for 14 days.
- Active ingredients
- Copper
manufacturer page · seachem.com · checked August 16, 2026
Record last checked August 16, 2026 · confidence high
Check against your tank
Change what is in your tank to see how the answer moves.
External parasite treatment (copper-amine) · US formulation
The manufacturer advises against using this with your tank.
At least one thing you listed is named in a warning. Move that livestock to another tank, or choose a different treatment.
- ShrimpManufacturer advises against
Seachem instructs keepers to remove all invertebrates before treatment, describing them as extremely sensitive to copper.
- SnailsManufacturer advises against
Snails are invertebrates and fall under the same instruction to remove all invertebrates before treatment.
- Live plantsNo evidence found
Seachem does not address live plants in its Cupramine documentation. No statement was found either way, so this stays unknown rather than being assumed safe.
See the manufacturer’s exact wording and sources for Seachem Cupramine →
No evidence found means no manufacturer statement was found — not that the product is safe. FishyMag does not diagnose disease or recommend treatments.
Other treatments
Next steps
FishyMag reports what manufacturers say, quoted and linked. It does not diagnose illness or recommend a treatment, and it never infers that a product is safe from the absence of a warning — where no statement exists, it says so.
Formulations change. Always read the label on the bottle in your hand, and contact the manufacturer if your tank contains anything valuable or unusual.