Compatibility library

Aquarium treatments

Every record is a specific formulation in a specific market, because the same brand name can be reformulated or sold differently elsewhere. Blank cells mean the manufacturer has not addressed that group—not that it is safe.

Aquarium evidence workbench with a blank notebook, water samples and measuring tools

24 formulations

TreatmentShrimpSnailsLive plantsScaleless fishMarine invertebratesBiological filter
Seachem ParaGuard
External parasite and fungal treatment
Do not useDo not useCautionCautionDo not use—
Fritz Aquatics Algae Clean Out
Algae treatment
Do not useDo not useCompatible—CompatibleUnknown
Fritz Aquatics Mardel Coppersafe
External parasite treatment (chelated copper)
Do not useDo not useCaution—Do not use—
Seachem Cupramine
External parasite treatment (copper-amine)
Do not useDo not useUnknown—Do not useUnknown
API Liquid Super Ick Cure
Ich treatment
Do not useConflictingUnknown—Do not use—
Seachem MetroPlex
Protozoan parasite and anaerobic bacterial treatment
Do not useDo not useUnknownUnknownUnknownUnknown
Seachem PolyGuard
Broad-spectrum bacterial, fungal and parasitic treatment
Do not useDo not useUnknownUnknownUnknownUnknown
Fritz Aquatics PraziCleanse
Anthelmintic (deworming) treatment
CautionCautionCompatibleUnknownUnknownUnknown
API General Cure
Internal and external parasite treatment
UnknownUnknownCompatible—Unknown—
Fritz Aquatics ParaCleanse
Internal parasite treatment
CompatibleCompatibleCompatible———
Seachem KanaPlex
Bacterial and fungal infection treatment
Do not useDo not useUnknown—Do not use—
Seachem NeoPlex
Bacterial infection treatment
ConflictingConflictingCaution——Compatible
Seachem Focus
Medication binder for medicated food
CautionUnknownCaution———
Seachem StressGuard
Slime coat protectant and stress reducer
CompatibleCompatibleCompatible—Compatible—
API MELAFIX
Antibacterial remedy
UnknownUnknownUnknown——Compatible
Fritz Aquatics Expel-P
Internal nematode treatment
CompatibleCautionCompatible—CautionConflicting
Fritz Aquatics Maracyn
Bacterial infection treatment
CompatibleCompatibleCaution—CompatibleDo not use
Seachem SulfaPlex
Bacterial and fungal infection treatment
Do not useDo not useUnknown———
API PIMAFIX
Antifungal remedy
CautionCautionUnknown—CompatibleCompatible
Fritz Aquatics Maracyn Two
Bacterial infection treatment
CompatibleCompatibleCaution—CompatibleCaution
Fritz Aquatics Maracyn Oxy
Non-antibiotic oxidising treatment
CompatibleCompatibleCautionCompatibleCaution—
Fritz Aquatics FixIck
External parasite treatment
Do not useDo not useCautionCompatibleDo not use—
Fritz Aquatics Expel-F
Antifungal / nuisance algae treatment
UnknownUnknown——Caution—
Fritz Aquatics MetroCleanse
Internal parasite treatment
UnknownUnknownUnknown———

FishyMag reports what manufacturers say, quoted and linked. It does not diagnose illness or recommend a treatment, and it never infers that a product is safe from the absence of a warning — where no statement exists, it says so.

Formulations change. Always read the label on the bottle in your hand, and contact the manufacturer if your tank contains anything valuable or unusual.