Compatibility library
Aquarium treatments
Every record is a specific formulation in a specific market, because the same brand name can be reformulated or sold differently elsewhere. Blank cells mean the manufacturer has not addressed that group—not that it is safe.
Evidence desk · illustrative24 formulations
| Treatment | Shrimp | Snails | Live plants | Scaleless fish | Marine invertebrates | Biological filter |
|---|---|---|---|---|---|---|
| Seachem ParaGuard External parasite and fungal treatment | Do not use | Do not use | Caution | Caution | Do not use | — |
| Fritz Aquatics Algae Clean Out Algae treatment | Do not use | Do not use | Compatible | — | Compatible | Unknown |
| Fritz Aquatics Mardel Coppersafe External parasite treatment (chelated copper) | Do not use | Do not use | Caution | — | Do not use | — |
| Seachem Cupramine External parasite treatment (copper-amine) | Do not use | Do not use | Unknown | — | Do not use | Unknown |
| API Liquid Super Ick Cure Ich treatment | Do not use | Conflicting | Unknown | — | Do not use | — |
| Seachem MetroPlex Protozoan parasite and anaerobic bacterial treatment | Do not use | Do not use | Unknown | Unknown | Unknown | Unknown |
| Seachem PolyGuard Broad-spectrum bacterial, fungal and parasitic treatment | Do not use | Do not use | Unknown | Unknown | Unknown | Unknown |
| Fritz Aquatics PraziCleanse Anthelmintic (deworming) treatment | Caution | Caution | Compatible | Unknown | Unknown | Unknown |
| API General Cure Internal and external parasite treatment | Unknown | Unknown | Compatible | — | Unknown | — |
| Fritz Aquatics ParaCleanse Internal parasite treatment | Compatible | Compatible | Compatible | — | — | — |
| Seachem KanaPlex Bacterial and fungal infection treatment | Do not use | Do not use | Unknown | — | Do not use | — |
| Seachem NeoPlex Bacterial infection treatment | Conflicting | Conflicting | Caution | — | — | Compatible |
| Seachem Focus Medication binder for medicated food | Caution | Unknown | Caution | — | — | — |
| Seachem StressGuard Slime coat protectant and stress reducer | Compatible | Compatible | Compatible | — | Compatible | — |
| API MELAFIX Antibacterial remedy | Unknown | Unknown | Unknown | — | — | Compatible |
| Fritz Aquatics Expel-P Internal nematode treatment | Compatible | Caution | Compatible | — | Caution | Conflicting |
| Fritz Aquatics Maracyn Bacterial infection treatment | Compatible | Compatible | Caution | — | Compatible | Do not use |
| Seachem SulfaPlex Bacterial and fungal infection treatment | Do not use | Do not use | Unknown | — | — | — |
| API PIMAFIX Antifungal remedy | Caution | Caution | Unknown | — | Compatible | Compatible |
| Fritz Aquatics Maracyn Two Bacterial infection treatment | Compatible | Compatible | Caution | — | Compatible | Caution |
| Fritz Aquatics Maracyn Oxy Non-antibiotic oxidising treatment | Compatible | Compatible | Caution | Compatible | Caution | — |
| Fritz Aquatics FixIck External parasite treatment | Do not use | Do not use | Caution | Compatible | Do not use | — |
| Fritz Aquatics Expel-F Antifungal / nuisance algae treatment | Unknown | Unknown | — | — | Caution | — |
| Fritz Aquatics MetroCleanse Internal parasite treatment | Unknown | Unknown | Unknown | — | — | — |
FishyMag reports what manufacturers say, quoted and linked. It does not diagnose illness or recommend a treatment, and it never infers that a product is safe from the absence of a warning — where no statement exists, it says so.
Formulations change. Always read the label on the bottle in your hand, and contact the manufacturer if your tank contains anything valuable or unusual.