Formulation evidence record

Seachem ParaGuard

External parasite and fungal treatment · US formulation

Shrimp

Amano, cherry, crystal and other freshwater shrimp.

Do not use

Snails

Nerite, mystery, ramshorn and other aquarium snails.

Do not use

Live plants

Rooted and floating live aquarium plants.

Caution

Scaleless fish

Loaches, corydoras, plecos, eels and other scaleless species.

Caution

Marine invertebrates

Corals, anemones, starfish and marine crustaceans.

Do not use

Not addressed by the manufacturer for: biological filter. No statement was found, so no verdict is given — that is not a clearance.

Why FishyMag says this

The manufacturer's own wording, quoted rather than paraphrased, so you can judge it yourself.

Shrimp

Manufacturer advises against

Seachem's Directions open by instructing keepers to remove all invertebrates before dosing. Their FAQ is softer — they decline to certify the product as invert safe rather than forbidding it — but an instruction in the Directions outranks a hedge in the FAQ, so this is recorded as advise-against.

Contains aldehydes, with a source-linked caution associated with this group. This raises a flag—it is not the basis of the verdict above.

Remove all invertebrates from the tank as well as any chemical filtration

manufacturer page · seachem.com · checked August 16, 2026

We do not sell or market ParaGuard™ as invert safe because it would be impossible to test it with every available invert under every potential water parameter.

manufacturer faq · seachem.com · checked August 16, 2026

Snails

Manufacturer advises against

Snails are invertebrates and fall under the same opening instruction in the Directions to remove all invertebrates before dosing.

Contains aldehydes, with a source-linked caution associated with this group. This raises a flag—it is not the basis of the verdict above.

Remove all invertebrates from the tank as well as any chemical filtration

manufacturer page · seachem.com · checked August 16, 2026

We do not sell or market ParaGuard™ as invert safe because it would be impossible to test it with every available invert under every potential water parameter.

manufacturer faq · seachem.com · checked August 16, 2026

Live plants

Caution

Seachem describes it as generally safe in planted aquaria, but frames this as their experience rather than a tested guarantee. That is weaker than a label claim, so it is recorded as caution rather than compatible.

generally safe to use in planted aquaria

manufacturer faq · seachem.com · checked August 16, 2026

Scaleless fish

Caution

Permitted, with an explicit instruction to start low. Seachem says scaleless species can be more sensitive and recommends beginning at a quarter to half dose before building up.

Contains malachite green, with a source-linked caution associated with this group. This raises a flag—it is not the basis of the verdict above.

You can use any of our medications with scaleless fish, but as they can be more sensitive, we would recommend that you begin with a 1/4 to 1/2 dose first and slowly build to the recommended dosage.

manufacturer faq · seachem.com · checked August 16, 2026

Marine invertebrates

Manufacturer advises against

Seachem states plainly that ParaGuard is not recommended for reef aquaria, alongside the Directions instruction to remove all invertebrates.

Contains aldehydes, with a source-linked caution associated with this group. This raises a flag—it is not the basis of the verdict above.

Remove all invertebrates from the tank as well as any chemical filtration

manufacturer page · seachem.com · checked August 16, 2026

We do not sell or market ParaGuard™ as invert safe because it would be impossible to test it with every available invert under every potential water parameter.

manufacturer faq · seachem.com · checked August 16, 2026

Product details

Manufacturer states it treats
External parasites, Fungal infections, Bacterial and viral lesions
Chemical filtration
Remove chemical filtration during treatment
Ingredients as stated
A proprietary, synergistic blend of aldehydes, malachite green and fish protective polymers (10% aldehydes by weight).
Active ingredients
AldehydesMalachite green

manufacturer page · seachem.com · checked August 16, 2026

Record last checked August 16, 2026 · confidence high

Check against your tank

Change what is in your tank to see how the answer moves.

External parasite and fungal treatment · US formulation

2 Select everything in the tank

Assuming a common community tank. Change the selection, or save your tank so every page answers for it.

The manufacturer advises against using this with your tank.

At least one thing you listed is named in a warning. Move that livestock to another tank, or choose a different treatment.

This answers for the assumed selection above, not a tank you have described. Adjust it if it is not yours.

  • ShrimpManufacturer advises against

    Seachem's Directions open by instructing keepers to remove all invertebrates before dosing. Their FAQ is softer — they decline to certify the product as invert safe rather than forbidding it — but an instruction in the Directions outranks a hedge in the FAQ, so this is recorded as advise-against.

  • SnailsManufacturer advises against

    Snails are invertebrates and fall under the same opening instruction in the Directions to remove all invertebrates before dosing.

  • Live plantsCaution

    Seachem describes it as generally safe in planted aquaria, but frames this as their experience rather than a tested guarantee. That is weaker than a label claim, so it is recorded as caution rather than compatible.

See the manufacturer’s exact wording and sources for Seachem ParaGuard

No evidence found means no manufacturer statement was found — not that the product is safe. FishyMag does not diagnose disease or recommend treatments.

Other treatments

Next steps

FishyMag reports what manufacturers say, quoted and linked. It does not diagnose illness or recommend a treatment, and it never infers that a product is safe from the absence of a warning — where no statement exists, it says so.

Formulations change. Always read the label on the bottle in your hand, and contact the manufacturer if your tank contains anything valuable or unusual.