Formulation evidence record

Seachem StressGuard

Slime coat protectant and stress reducer · US formulation

Shrimp

Amano, cherry, crystal and other freshwater shrimp.

Compatible

Snails

Nerite, mystery, ramshorn and other aquarium snails.

Compatible

Live plants

Rooted and floating live aquarium plants.

Compatible

Marine invertebrates

Corals, anemones, starfish and marine crustaceans.

Compatible

Not addressed by the manufacturer for: scaleless fish, biological filter. No statement was found, so no verdict is given — that is not a clearance.

Why FishyMag says this

The manufacturer's own wording, quoted rather than paraphrased, so you can judge it yourself.

Shrimp

Manufacturer states compatible

Seachem states StressGuard is safe in a reef or planted aquarium containing invertebrates when dosed as instructed.

“Yes, as long as StressGuard™ is dosed according to the instructions, it is safe to use in a reef or planted aquarium containing invertebrates.”

manufacturer page · seachem.com · checked August 16, 2026

Snails

Manufacturer states compatible

Covered by the same invertebrate safety statement.

“Yes, as long as StressGuard™ is dosed according to the instructions, it is safe to use in a reef or planted aquarium containing invertebrates.”

manufacturer page · seachem.com · checked August 16, 2026

Live plants

Manufacturer states compatible

Planted aquaria are named explicitly in the same statement.

“Yes, as long as StressGuard™ is dosed according to the instructions, it is safe to use in a reef or planted aquarium containing invertebrates.”

manufacturer page · seachem.com · checked August 16, 2026

Marine invertebrates

Manufacturer states compatible

Reef aquaria are named explicitly in the safety statement.

“Yes, as long as StressGuard™ is dosed according to the instructions, it is safe to use in a reef or planted aquarium containing invertebrates.”

manufacturer page · seachem.com · checked August 16, 2026

Do not combine with

Documented incompatibilities only. A treatment absent from this list has not been cleared to run alongside anything — it simply has no published warning.

Seachem Cupramine

Seachem states StressGuard is compatible with all medications except copper-based ones, naming Cupramine directly. Do not run the two together.

“StressGuard™ is compatible with all medications, EXCEPT those that are copper based, including Seachem Cupramine™.”

manufacturer page · seachem.com · checked August 16, 2026

Product details

Manufacturer states it treats: Reducing stress, Protecting the slime coat, Aiding healing
Chemical filtration: Chemical filtration can stay in

manufacturer page · seachem.com · checked August 16, 2026

Record last checked August 16, 2026 · confidence high

Check against your tank

Change what is in your tank to see how the answer moves.

1 Choose the treatment

Slime coat protectant and stress reducer · US formulation

2 Select everything in the tank

Assuming a common community tank. Change the selection, or save your tank so every page answers for it.

The manufacturer states this is compatible with everything you listed.

Still read the bottle in your hand — formulations change, and your bottle may be a different revision from the one documented.

This answers for the assumed selection above, not a tank you have described. Adjust it if it is not yours.

ShrimpManufacturer states compatible
Seachem states StressGuard is safe in a reef or planted aquarium containing invertebrates when dosed as instructed.
SnailsManufacturer states compatible
Covered by the same invertebrate safety statement.
Live plantsManufacturer states compatible
Planted aquaria are named explicitly in the same statement.

See the manufacturer’s exact wording and sources for Seachem StressGuard →

No evidence found means no manufacturer statement was found — not that the product is safe. FishyMag does not diagnose disease or recommend treatments.

Next steps

How much Seachem StressGuard for my tank?Scales the label ratio to your real water volume, with the manufacturer wording beside the answer.Check against my tankSee how Seachem StressGuard and every other treatment compare against what you actually keep.Compare with another treatmentPut Seachem StressGuard beside up to three alternatives, group by group.Work out your real water volumeDose against the water your tank holds, not the number on the box.

FishyMag reports what manufacturers say, quoted and linked. It does not diagnose illness or recommend a treatment, and it never infers that a product is safe from the absence of a warning — where no statement exists, it says so.

Formulations change. Always read the label on the bottle in your hand, and contact the manufacturer if your tank contains anything valuable or unusual.