Label case studies
StressGuard: a livestock statement is not permission to combine products
Why the invertebrate answer and copper-medication restriction address different questions.
Formulation evidence record
Seachem StressGuard
Slime coat protectant and stress reducer · US formulation
Shrimp
Amano, cherry, crystal and other freshwater shrimp.
Snails
Nerite, mystery, ramshorn and other aquarium snails.
Live plants
Rooted and floating live aquarium plants.
Marine invertebrates
Corals, anemones, starfish and marine crustaceans.
Not addressed by the manufacturer for: scaleless fish, biological filter. No statement was found, so no verdict is given — that is not a clearance.
Why FishyMag says this
The manufacturer's own wording, quoted rather than paraphrased, so you can judge it yourself.
Shrimp
Manufacturer states compatibleSeachem states StressGuard is safe in a reef or planted aquarium containing invertebrates when dosed as instructed.
“Yes, as long as StressGuard™ is dosed according to the instructions, it is safe to use in a reef or planted aquarium containing invertebrates.”
manufacturer page · seachem.com · checked August 16, 2026
Snails
Manufacturer states compatibleCovered by the same invertebrate safety statement.
“Yes, as long as StressGuard™ is dosed according to the instructions, it is safe to use in a reef or planted aquarium containing invertebrates.”
manufacturer page · seachem.com · checked August 16, 2026
Live plants
Manufacturer states compatiblePlanted aquaria are named explicitly in the same statement.
“Yes, as long as StressGuard™ is dosed according to the instructions, it is safe to use in a reef or planted aquarium containing invertebrates.”
manufacturer page · seachem.com · checked August 16, 2026
Marine invertebrates
Manufacturer states compatibleReef aquaria are named explicitly in the safety statement.
“Yes, as long as StressGuard™ is dosed according to the instructions, it is safe to use in a reef or planted aquarium containing invertebrates.”
manufacturer page · seachem.com · checked August 16, 2026
Check the evidence boundary
What this record can—and cannot—answer
Bottle identity
US formulation · label revision: not recorded · version: not recorded.
Match the label and concentration on your bottle before using a dose ratio.
Unresolved groups
Scaleless fish, Biological filter
Missing evidence is not a compatibility finding.
Product combinations
1 specific warning(s) recorded below. This is not a complete interaction review or permission to combine treatments.
Evidence age
Formulation record checked August 16, 2026. Source dates can differ within the record. A dated check is not a guarantee that the label has stayed unchanged.
Do not combine with
Documented incompatibilities only. A treatment absent from this list has not been cleared to run alongside anything — it simply has no published warning.
Seachem Cupramine
Seachem states StressGuard is compatible with all medications except copper-based ones, naming Cupramine directly. Do not run the two together.
“StressGuard™ is compatible with all medications, EXCEPT those that are copper based, including Seachem Cupramine™.”
manufacturer page · seachem.com · checked August 16, 2026
Product details
- Manufacturer states it treats
- Reducing stress, Protecting the slime coat, Aiding healing
- Chemical filtration
- Chemical filtration can stay in
manufacturer page · seachem.com · checked August 16, 2026
Record last checked August 16, 2026 · confidence high
Check against your tank
Change what is in your tank to see how the answer moves.
The biological filter is included in every non-empty tank check, alongside your selected groups.
Slime coat protectant and stress reducer · US formulation
The manufacturer has not addressed part of your tank.
Silence is not a clearance. Where no statement exists, treat it as unconfirmed and ask the manufacturer.
This answers for the assumed selection above, not a tank you have described. Adjust it if it is not yours.
- ShrimpManufacturer states compatible
Seachem states StressGuard is safe in a reef or planted aquarium containing invertebrates when dosed as instructed.
- SnailsManufacturer states compatible
Covered by the same invertebrate safety statement.
- Live plantsManufacturer states compatible
Planted aquaria are named explicitly in the same statement.
- Biological filterNo evidence found
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
See the manufacturer’s exact wording and sources for Seachem StressGuard →
No evidence found means no manufacturer statement was found — not that the product is safe. FishyMag does not diagnose disease or recommend treatments.
Other treatments
Seachem ParaGuardFritz Aquatics Algae Clean OutFritz Aquatics Mardel CoppersafeSeachem CupramineAPI Liquid Super Ick CureSeachem MetroPlexSeachem PolyGuardFritz Aquatics PraziCleanseAPI General CureFritz Aquatics ParaCleanseSeachem KanaPlexSeachem NeoPlexSeachem FocusAPI MELAFIXFritz Aquatics Expel-PFritz Aquatics MaracynSeachem SulfaPlexAPI PIMAFIXFritz Aquatics Maracyn TwoFritz Aquatics Maracyn OxyFritz Aquatics FixIckFritz Aquatics Expel-FFritz Aquatics MetroCleanse
Understand the label in context
Next steps
Does this record match your bottle?Compare the name, market and label details. Download unresolved identity questions.Resolve an unanswered question about Seachem StressGuardDownload the evidence and a manufacturer enquiry with your bottle details and livestock groups.Keep a treatment recordRecord what was actually used and when. Save on this device or export for a support conversation.How much Seachem StressGuard for my tank?Scales the label ratio to your real water volume, with the manufacturer wording beside the answer.Check against my tankSee how Seachem StressGuard and every other treatment compare against what you actually keep.Compare with another treatmentPut Seachem StressGuard beside up to three alternatives, group by group.Work out your real water volumeDose against the water your tank holds, not the number on the box.
FishyMag reports what manufacturers say, quoted and linked. It does not diagnose illness or recommend a treatment, and it never infers that a product is safe from the absence of a warning — where no statement exists, it says so.
Formulations change. Always read the label on the bottle in your hand, and contact the manufacturer if your tank contains anything valuable or unusual.