Compatibility index
Which aquarium treatments are safe for scaleless fish?
Loaches, corydoras, plecos, eels and other scaleless species. Every treatment in the database, grouped by what its manufacturer actually states — not by what the ingredient list implies.
2 of 24 formulations are stated compatible with scaleless fish by the manufacturer.
The rest are qualified, contradicted, or simply never addressed — which is why counting green ticks is the wrong way to read this page.
The manufacturer states it is compatible (2)
A positive claim from the people who make the product. This is the only group where a manufacturer has actually said yes.
Fritz Aquatics Maracyn Oxy
Non-antibiotic oxidising treatment
Scaleless species are listed as compatible without a reduced-dose instruction, which is unusual — most treatments hedge here.
Fritz Aquatics FixIck
External parasite treatment
Scaleless species are marked compatible, which is notable for a dye-based parasite treatment — the class most often flagged as hard on them.
Permitted, with conditions (1)
Not a refusal and not a clearance — a reduced dose, a species carve-out, or a manufacturer declining to certify.
No statement found (21)
We looked and the manufacturer does not address this group. Silence is not a clearance — treat these as unconfirmed.
Fritz Aquatics Algae Clean Out
Algae treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Fritz Aquatics Mardel Coppersafe
External parasite treatment (chelated copper)
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Seachem Cupramine
External parasite treatment (copper-amine)
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
API Liquid Super Ick Cure
Ich treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Seachem MetroPlex
Protozoan parasite and anaerobic bacterial treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check before dosing.
Seachem PolyGuard
Broad-spectrum bacterial, fungal and parasitic treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check before dosing.
Fritz Aquatics PraziCleanse
Anthelmintic (deworming) treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check before dosing.
API General Cure
Internal and external parasite treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Fritz Aquatics ParaCleanse
Internal parasite treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Seachem KanaPlex
Bacterial and fungal infection treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Seachem NeoPlex
Bacterial infection treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Seachem Focus
Medication binder for medicated food
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Seachem StressGuard
Slime coat protectant and stress reducer
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
API MELAFIX
Antibacterial remedy
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Fritz Aquatics Expel-P
Internal nematode treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Fritz Aquatics Maracyn
Bacterial infection treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Seachem SulfaPlex
Bacterial and fungal infection treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
API PIMAFIX
Antifungal remedy
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Fritz Aquatics Maracyn Two
Bacterial infection treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Fritz Aquatics Expel-F
Antifungal / nuisance algae treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Fritz Aquatics MetroCleanse
Internal parasite treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Other livestock
No evidence found means no manufacturer statement was found, not that a product is safe. Dataset last checked August 16, 2026.
FishyMag reports what manufacturers say, quoted and linked. It does not diagnose illness or recommend a treatment, and it never infers that a product is safe from the absence of a warning — where no statement exists, it says so.
Formulations change. Always read the label on the bottle in your hand, and contact the manufacturer if your tank contains anything valuable or unusual.