Compatibility index
Which aquarium treatments are safe for live plants?
Rooted and floating live aquarium plants. Every treatment in the database, grouped by what its manufacturer actually states — not by what the ingredient list implies.
6 of 24 formulations are stated compatible with live plants by the manufacturer.
The rest are qualified, contradicted, or simply never addressed — which is why counting green ticks is the wrong way to read this page.
The manufacturer states it is compatible (6)
A positive claim from the people who make the product. This is the only group where a manufacturer has actually said yes.
Fritz Aquatics Algae Clean Out
Algae treatment
Fritz states it is safe for planted systems and will not harm live plants when used as directed.
Fritz Aquatics PraziCleanse
Anthelmintic (deworming) treatment
Fritz states directly that it does not harm plants — an unqualified, taxon-specific claim rather than the hedged wording used for invertebrates.
API General Cure
Internal and external parasite treatment
API states directly that General Cure is safe for use with live plants.
Fritz Aquatics ParaCleanse
Internal parasite treatment
Fritz states the product does not harm plants.
Seachem StressGuard
Slime coat protectant and stress reducer
Planted aquaria are named explicitly in the same statement.
Fritz Aquatics Expel-P
Internal nematode treatment
Fritz states the product does not harm plants.
Permitted, with conditions (8)
Not a refusal and not a clearance — a reduced dose, a species carve-out, or a manufacturer declining to certify.
Seachem ParaGuard
External parasite and fungal treatment
Seachem describes it as generally safe in planted aquaria, but frames this as their experience rather than a tested guarantee. That is weaker than a label claim, so it is recorded as caution rather than compatible.
Fritz Aquatics Mardel Coppersafe
External parasite treatment (chelated copper)
Fritz flags possible harm to plants and amphibians rather than ruling it out entirely, so a planted tank is a judgement call rather than a clear yes or no.
Seachem NeoPlex
Bacterial infection treatment
Rather than clearing plants, Seachem steers planted-tank keepers toward medicating through Focus-bound frozen food to keep medication out of the water column.
Seachem Focus
Medication binder for medicated food
Same reasoning: Seachem presents food-bound dosing as a way to avoid damaging delicate plants, without certifying Focus itself as plant safe.
Fritz Aquatics Maracyn
Bacterial infection treatment
Compatible with a stated cosmetic caveat — Fritz warns some plant species may yellow temporarily. Recorded as caution rather than compatible because the manufacturer attaches a visible effect to its own yes.
Fritz Aquatics Maracyn Two
Bacterial infection treatment
Cleared, but with a cosmetic caveat the manufacturer attaches to its own yes: some species may yellow temporarily.
Fritz Aquatics Maracyn Oxy
Non-antibiotic oxidising treatment
Cleared with the same yellowing caveat Fritz attaches across the Maracyn range.
Fritz Aquatics FixIck
External parasite treatment
Fritz refuses a straight yes or no here and says tolerance depends on the species — an honest answer, and one that means a planted tank is a judgement call rather than a clearance.
No statement found (10)
We looked and the manufacturer does not address this group. Silence is not a clearance — treat these as unconfirmed.
Seachem Cupramine
External parasite treatment (copper-amine)
Seachem does not address live plants in its Cupramine documentation. No statement was found either way, so this stays unknown rather than being assumed safe.
API Liquid Super Ick Cure
Ich treatment
No manufacturer statement about live plants was found for this formulation.
Seachem MetroPlex
Protozoan parasite and anaerobic bacterial treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check before dosing.
Seachem PolyGuard
Broad-spectrum bacterial, fungal and parasitic treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check before dosing.
Seachem KanaPlex
Bacterial and fungal infection treatment
Seachem does not address live plants in its KanaPlex documentation. No statement was found either way.
API MELAFIX
Antibacterial remedy
No statement about live plants was found on API’s product page.
Seachem SulfaPlex
Bacterial and fungal infection treatment
Seachem does not address live plants for this product.
API PIMAFIX
Antifungal remedy
API makes no statement about live plants for this product.
Fritz Aquatics Expel-F
Antifungal / nuisance algae treatment
No statement from the manufacturer was found for this group. Treat it as unconfirmed and check with the manufacturer before dosing.
Fritz Aquatics MetroCleanse
Internal parasite treatment
No manufacturer statement about live plants was found for this formulation.
Other livestock
No evidence found means no manufacturer statement was found, not that a product is safe. Dataset last checked August 16, 2026.
FishyMag reports what manufacturers say, quoted and linked. It does not diagnose illness or recommend a treatment, and it never infers that a product is safe from the absence of a warning — where no statement exists, it says so.
Formulations change. Always read the label on the bottle in your hand, and contact the manufacturer if your tank contains anything valuable or unusual.